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APHER2NEU
HER-2 / NEU (C-ERB-B2), IMMUNOHISTOCHEMISTRY STAIN

Test Code APHER2NEU 
Test HER-2 / neu (C-erb-B2), IMMUNOHISTOCHEMISTRY STAIN 
Methodology Avidin-Biotin Complex Method Immunohistochemistry Stain 
Description C-erb-B2 oncoprotein (HER-2/neu) is a trans-membrane glycoprotein expressed in breast and many other adenocarcinomas, as well as transitional cell carcinoma. In some cases, tumor aggressiveness and state of differentiation have been correlated to the amplified expression of this protein in breast carcinoma. In breast cancer, C-erb-B2 expression is a marker of poor prognosis and may predict response to treatment.

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist. 

Specimen Formalin-fixed or paraffin-embedded tissue specimen. 
Reference Values An interpretive report will be issued. 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 88342