|Test||HER-2 / neu (C-erb-B2), IMMUNOHISTOCHEMISTRY STAIN|
|Methodology||Avidin-Biotin Complex Method Immunohistochemistry Stain|
|Description||C-erb-B2 oncoprotein (HER-2/neu) is a trans-membrane glycoprotein expressed in breast and many other adenocarcinomas, as well as transitional cell carcinoma. In some cases, tumor aggressiveness and state of differentiation have been correlated to the amplified expression of this protein in breast carcinoma. In breast cancer, C-erb-B2 expression is a marker of poor prognosis and may predict response to treatment.
NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist.
|Specimen||Formalin-fixed or paraffin-embedded tissue specimen.|
|Reference Values||An interpretive report will be issued.|
|Analytic Time||2 Days|
|Day(s) Test Set Up||Monday through Friday|