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PROF3
ARTHRITIS/SLE PANEL

Test Code PROF3 
Test ARTHRITIS/SLE PANEL 
Methodology Indirect Immunofluorescence / Turbidimetric Immunoassay / Electrophoresis / Immunofixation 
Description Useful for the overall assessment of a patient's protein status; often utilized if autoimmune, lymphoproliferative, or immunodeficiency disorders are suspected.

Includes:
Albumin
Alpha-1-Antitrypsin
Anti ds-DNA (if indicated)
Antinuclear Antibodies (ANA)
C3
C4
C-Reactive Protein (CRP)
Haptoglobin
Immunofixation (if indicated)
Immunoglobulins (IgG, IgA, and IgM)
Prealbumin
Protein Electrophoresis
Protein, Total
Rheumatoid Factor
Transferrin
An ANA titer will automatically be performed if the ANA screen is positive, and an anti ds-DNA will automatically be performed at an additional charge if the ANA titer is >= 1:160. Immunofixation will be performed as needed to characterize monoclonal proteins at an additional charge.

NOTE: Tests may be ordered individually.

NOTE: This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policy "Serum Iron Studies". Please verify that the diagnosis code (ICD-9) you have chosen demonstrates medical necessity for the test as documented in the physician's patient record. The CMS web site or the NorDx Limited Coverage Documentation Guide are available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD-9 code chosen or if the frequency of a frequency-limited test is unknown.

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately. 

Specimen Draw blood in either a plain, red-top tube or serum gel tube. (PLASMA OR GROSSLY LIPEMIC SPECIMEN IS NOT ACCEPTABLE.) Spin down promptly and send 3.0 mL (minimum volume: 1.0 mL) of serum refrigerated. 
Reference Values An interpretive report will be issued. 
Analytic Time 3 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 82040  Albumin
82103  Alpha-1-antitrypsin
82784 x 3  Immunoglobulins, each
83010  Haptoglobin
84134  Prealbumin
84155  Protein, total
84165  Protein electrophoresis
84165-26  Professional component protein electrophoresis
84466  Transferrin
86038  ANA screen
86039  ANA titer, if indicated
86140  C-reactive protein
86160 x 2  Complement, each component
86225  Anti ds-DNA, if indicated
86334  Immunofixation, if indicated
86334-26  Professional component, immunofixation, if applicable.
86431  Rheumatoid factor