|Test||FATTY ACID PROFILE, MITOCHONDRIAL (C8-C18), SERUM|
|Methodology||Gas Chromatography / Mass Spectrometry (GC-MS), Stable Isotope Dilution Analysis|
|Description||Useful for diagnosis of inborn errors of mitochondrial fatty acid oxidation, including deficiencies of medium-chain acyl-Co-A dehydrogenase, long-chain 3-hydroxyacyl-Co-A dehydrogenase, very long-chain acyl-Co-A dehydrogenase, and glutaric acidemia type 2. Treatment of essential fatty acid deficiency depends on the cause of the disorder and may include nutritional supplementation of essential fatty acids, linoleic acid (C18:2w6) and alpha-linolenic acid (C18:3w3).|
|Specimen||Draw blood in a plain, red-top tube or serum gel following an overnight (12 - 24 hour) fast. Patient must not consume any alcohol for 24 hours before the specimen is drawn. Spin down and send 0.5 mL (minimum: 0.2 mL) of serum FROZEN in plastic vial on dry ice.
|Reference Values||See "Fatty Acid Reference Values.'|
|Analytic Time||3 Days|
|Day(s) Test Set Up||Monday through Friday|