|Test||UROPORPHYRINOGEN III SYNTHASE (CO-SYNTHASE) (Upg III S), ERYTHROCYTES|
|Methodology||High Performance Liquid Chromatography (HPLC)
Note: This test measures UPG III synthase to diagnose
congenital erythropoietic porphyria. It does not
measure UPG I synthase, the enzyme deficiency
responsible for acute intermittent porphyria (AIP).
For AIP (and UPG I synthase), order #88925
"Porphobilinogen (PBG) Deaminase, Erythrocytes."
See "Porphyria (Acute) Testing Algorithm" and
"Porphyria (Cutaneous) Testing Algorithm" in
Special Instructions for additional information.
|Description||Useful for investigation of the feasibility of CEP and as the basis for biochemical diagnosis of CEP|
|Specimen||All porphyrin tests on erythrocytes can be performed on 1 draw
Specimen must arrive within 48 hours of draw.
1. Patient should abstain from alcohol for 24 hours.
|Reference Values||>= 75 Relative Units (normal)
See "Porphyrinogens, Porphyrins, and Porphyrias."
|Analytic Time||7 Days|
|Day(s) Test Set Up||Varies|