Home


8652M
INHERITED CONJUGATED HYPERBILIRUBINEMIAS, 24-HOUR URINE

Test Code 8652M 
Test INHERITED CONJUGATED HYPERBILIRUBINEMIAS, 24-HOUR URINE 
Methodology High - Pressure Liquid Chromatography (HPLC) 
Description Useful for evaluation of chronic liver disease and aids in diagnosis of Dubin - Johnson syndrome and in diagnosis of Rotor syndrome. 
Specimen 20 - 50 mL (minimum: 10 mL) from a 24-hour urine collection. Add 5 g of sodium carbonate as preservative at start of collection. (ACCEPTABLE PRESERVATIVE MUST BE ADDED AT THE START OF COLLECTION.) This preservative is intended to achieve a pH of > 7.0. See "Urine Preservatives" for multiple collections. Send specimen FROZEN in a plastic, 60-mL urine bottle on dry ice. PROTECT SPECIMEN FROM LIGHT.

NOTE:
1. DO NOT SUBSTITUTE SODIUM BICARBONATE FOR SODIUM CARBONATE.
2. The pH will generally fall between 8 - 10 if the proper preservative (5 g sodium carbonate) was added to the container before the collection was started.
3. The patient should be off medications for at least 1 week. If clinically inappropriate to discontinue medications, forward a list of medications with the specimen.
4. Patient should abstain from alcohol and caffeine containing beverages for at least 24 hours before as well as during the collection period.
5. 24-HOUR VOLUME IS REQUIRED ON REQUEST FORM FOR PROCESSING. 

Reference Values TOTAL COPROPORPHYRINS
<16 years: not established
Males: 25-150 ug/24 hours
Females: 8-110 ug/24 hours

% COPROPORPHYRIN I
<16 years: not established
>= 16 years: 20-45% 

Analytic Time 3 Days 
Day(s) Test Set Up Varies 
CPT Code(s) 84120  

Special Instructions