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DHEAS / DHES-M
DEHYDROEPIANDROSTERONE SULFATE (DHEA-S), SERUM

Test Code DHEAS / DHES-M 
Test DEHYDROEPIANDROSTERONE SULFATE (DHEA-S), SERUM 
Methodology Immunochemiluminescent Assay (ICMA) 
Description Useful for the diagnosis of congenital adrenal hyperplasia and adrenal carcinoma, and for determining the cause of hirsutism, virilization, and polycystic ovary disease. 
Specimen Draw blood in a plain, red-top tube or serum gel tube. Spin down and send 0.5 mL (minimum: 0.3 mL) of serum refrigerated in plastic vial. 
Reference Values MALES
1-14 days: DHEA-S levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days.

*Tanner Stage: [Mean Age] Reference Range
Stage I: [>14 days] <15-120 g/dL
Stage II: [11.5 years] <15-333 g/dL
Stage III: [13.6 years] <15-312 g/dL
Stage IV: [15.1 years] 29-412 g/dL
Stage V: [18.0 years] 89-457 g/dL

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for boys at a median age of 11.5 (+/-) 2 years. For boys, there is no proven relationship between puberty onset and body weight or ethnic origin. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.

18-29 years: 89-457 g/dL
30-39 years: 65-334 g/dL
40-49 years: 48-244 g/dL
50-59 years: 35-179 g/dL
> or = 60 years: 25-131 g/dL

FEMALES
1-14 days: DHEA-S levels in newborns are very elevated at birth but will fall to prepubertal levels within a few days.

*Tanner Stage: [Mean Age] Reference Range
Stage I: [>14 days] 16-96 g/dL
Stage II: [10.5 years] 22-184 g/dL
Stage III: [11.6 years] <15-296 g/dL
Stage IV: [12.3 years] 17-343 g/dL
Stage V: [14.5 years] 44-332 g/dL

*Puberty onset (transition from Tanner stage I to Tanner stage II) occurs for girls at a median age of 10.5 (+/-) 2 years. There is evidence that it may occur up to 1 year earlier in obese girls and in African-American girls. Progression through Tanner stages is variable. Tanner stage V (adult) is usually reached by age 18.

18-29 years: 44-332 g/dL
30-39 years: 31-228 g/dL
40-49 years: 18-244 g/dL
50-59 years: <15-200 g/dL
> or = 60 years: <15-157 g/dL 

Analytic Time 1 Day 
Day(s) Test Set Up Monday, Wednesday, Friday 
CPT Code(s) 82627