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CK-5/6
CYTOKERATIN 5 / 6 IMMUNOHISTOCHEMISTRY STAIN

Test Code CK-5/6 
Test CYTOKERATIN 5 / 6 IMMUNOHISTOCHEMISTRY STAIN 
Description Cytokeratin 5/6 reacts with cytokeratins with molecular weight of 58kDa and 56kDa. It stains the basal cells of squamous and glandular epithelia, the stratum spinosum of squamous epithelium, myoepithelium and mesothelium. It does not, however, stain glandular epithelium. Therefore, the Cytokeratin 5/6 antibody can be used to distinguish squamous cell carcinoma (positive) from adenocarcinoma (negative), and to differentiate epithelial mesothelioma (positive) from non-epithelial mesothelioma and adenocarcinoma (negative).

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist. 

Specimen Formalin-fixed or paraffin-embedded tissue specimen 
Reference Values An interpretive report will be issued. 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 88342