Home


APCD68
CD68 / MACROPHAGE (KP1), IMMUNOHISTOCHEMISTRY STAIN

Test Code APCD68 
Test CD68 / MACROPHAGE (KP1), IMMUNOHISTOCHEMISTRY STAIN 
Description KP1 antibody (CD68) reacts with tangible macrophages, interdigitating macrophages of lymph nodes and tissue macrophages from various sources such as Kupffer cells of the liver and alveolar macrophages of the lung. It also stains peripheral blood monocytes and granulocytes, myeloid precursors, mast cells, and osteoclasts. KP1 stains a cell population known as "plasmacytoid T cells" which are present in many reactive lymph nodes. This antibody may be useful for the identificaton of myelomonocytic and histiocytic malignancies. It may also help distinguish malignant fibrohistiocytoma from other pleomorphic sarcomas. KP1 has been shown to stain a variable number of cells in malignant melanomas. Neoplasms of lymphoid origin are usually negative, although some B-cell neoplasms such as small lymphocytic lymphoma and hairy cell leukemia may show weak granular staining of the cytoplasm.

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist. 

Specimen Formalin-fixed or paraffin-embedded tissue specimen. 
Reference Values An interpretive report will be issued. 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 88342