|Test Code||CLONA / CZPS-M|
|Test||CLONAZEPAM + 7-AMINOCLONAZEPAM|
|Methodology||Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)|
Monitoring for appropriate therapeutic level
|Specimen||1.2 mL in a plain, red top tube
Draw specimen immediately before next scheduled dose (minimum 12 hours after last dose).
Serum must be separated from cells within 2 hours of draw.
Anticonvulsant: 20-70 ng/mL
Anxiolytic: 4-80 ng/mL
Some individuals may show therapeutic response outside of these ranges, or may display toxicity within the therapeutic range, thus interpretation should include clinical evaluation.
Note: Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens
|Analytic Time||2 Days|
|Day(s) Test Set Up||Tuesday, Thursday; 1 a.m.|
G0480 (if appropriate)