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CLONA / CZPS-M
CLONAZEPAM + 7-AMINOCLONAZEPAM

Test Code CLONA / CZPS-M 
Test CLONAZEPAM + 7-AMINOCLONAZEPAM 
Methodology Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) 
Description Assessing compliance
Monitoring for appropriate therapeutic level
Assessing toxicity 
Specimen 1.2 mL in a plain, red top tube
Draw specimen immediately before next scheduled dose (minimum 12 hours after last dose).
Serum must be separated from cells within 2 hours of draw. 
Reference Values Clonazepam
Anticonvulsant: 20-70 ng/mL
Anxiolytic: 4-80 ng/mL
Some individuals may show therapeutic response outside of these ranges, or may display toxicity within the therapeutic range, thus interpretation should include clinical evaluation.

Note: Therapeutic ranges are for specimens drawn at trough (ie, immediately before next scheduled dose). Levels may be elevated in non-trough specimens 

Analytic Time 2 Days 
Day(s) Test Set Up Tuesday, Thursday; 1 a.m. 
CPT Code(s) 80346  
G0480 (if appropriate)