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CHMAB / CMACB-M
CHROMOSOMAL MICROARRAY, CONGENITAL, BLOOD

Test Code CHMAB / CMACB-M 
Test CHROMOSOMAL MICROARRAY, CONGENITAL, BLOOD 
Methodology Chromosomal Microarray, Blood 
Description First tier, postnatal test for individuals with multiple anomalies that are not specific to well-delineated genetic syndromes, apparently nonsyndromic developmental delay or intellectual disability, or autism spectrum disorders as recommended by the American College of Medical Genetics (ACMG).

An appropriate follow-up test for individuals with unexplained developmental delay or intellectual disability, autism spectrum disorders, or congenital anomalies with a previously normal conventional chromosome study

Determining the size, precise breakpoints, gene content, and any unappreciated complexity of abnormalities detected by other methods such as conventional chromosome and FISH studies

Determining if apparently balanced abnormalities identified by previous conventional chromosome studies have cryptic imbalances, since a proportion of such rearrangements that appear balanced at the resolution of a chromosome study are actually unbalanced when analyzed by higher-resolution chromosomal microarray.

Assessing regions of homozygosity related to uniparental disomy or identity by descent. 
Specimen 3 mLs (2 mLs minimum) Whole Blood from a Sodium Hep Green Top and an EDTA Lavender Top, Room temperature.

Invert several times to mix blood
Send specimens in original tubes

** Both a whole blood EDTA and a whole blood sodium heparin specimen are required. 

Reference Values An interpretive report will be provided 
Analytic Time 10 to 12 Days 
Day(s) Test Set Up Samples processed Monday through Sunday. Results reported Monday through Friday; 9 a.m.- 6 p.m. 
CPT Code(s) 81229