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CHHBM/CHRBM-M
CHROMOSOME ANALYSIS HEMATOLOGIC DISORDERS, BONE MARROW

Test Code CHHBM/CHRBM-M 
Test CHROMOSOME ANALYSIS HEMATOLOGIC DISORDERS, BONE MARROW 
Methodology Cell Culture without Mitogens* followed by Chromosome Analysis

*In addition to the cell culture without mitogens, a CpG-stimulated culture will be added and 10 additional cells will be analyzed for any specimen received from a patient age 30 or older with a reason for referral of chronic lymphocytic leukemia, small lymphocytic leukemia, lymphocytosis, Waldenstrom macroglobulinemia, or when test CLLF / Chronic Lymphocytic Leukemia (CLL), FISH is ordered concurrently. 

Description Useful for:

Assisting in the diagnosis and classification of certain malignant hematological disorders

Evaluation of prognosis in patients with certain malignant hematologic disorders

Monitoring effects of treatment

Monitoring patients in remission 

Specimen Provide a reason for referral with each specimen. The laboratory will not reject testing if this information is not provided, but appropriate testing and interpretation may be compromised or delayed.

Specimen Type: Bone Marrow
Container/Tube: Green top (sodium heparin)
Specimen Volume: 2-3 mL Bone Marrow
Collection Instructions:
1. It is preferable to send the first aspirate from the bone marrow collection.
2. Invert several times to mix bone marrow.
3. Other anticoagulants are not recommended and are harmful to the viability of the cells. 

Reference Values An interpretative report will be provided 
Analytic Time 9 to 10 Days 
Day(s) Test Set Up Samples processed Monday through Sunday. Results reported Monday through Friday; 8 a.m. to 5 p.m. 
CPT Code(s) 88237  
88264 (if appropriate)  
88265 (if appropriate)  
88283 (if appropriate)  
88285 (if appropriate)  
88291