|Test||ALDOSTERONE 24 HOUR URINE|
|Methodology||Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)|
|Description||Useful for investigation of primary aldosteronism (eg, adrenal adenoma/carcinoma and adrenal cortical hyperplasia) and secondary aldosteronism (renovascular disease, salt depletion, potassium loading, cardiac failure with ascites, pregnancy, Bartter syndrome)|
|Specimen||10 mL from a 24-hour urine collection.
Add 25 mL of 50% acetic acid as preservative at start of collection. Use 15 mL of 50% acetic acid for children <5 years old. This preservative is intended to achieve a pH of between approximately 2 and 4.
|Reference Values||0-30 days: 0.7-11.0 mcg/24 hours*
31 days-11 months: 0.7-22.0 mcg/24 hours*
> or =1 year: 2.0-20.0 mcg/24 hours
*Loeuille GA, Racadot A, Vasseur P, Vandewalle B: Blood and urinary aldosterone levels in normal neonates, infants and children. Pediatrie 1981;36:335-344
|Analytic Time||2-3 Days|
|Day(s) Test Set Up||Monday, Thursday; 3 p. m.|