Test Code CKMB 
Methodology Electro chemiluminescence immunoassay “ECLIA” 
Description DESCRIPTION: Immunoassay for the invitro quantitative determination of the MB isoenzyme of creatine kinase in human serum and plasma. The determination of CK-MB mass in serum is an important element in the diagnosis of myocardial ischemia, e.g. in acute myocardial infarction, myocarditis, etc.

No sample should be collected on patients receiving therapy with high biotin doses(i.e. biotin therapy for Multiple Sclerosis or oncology patients; skin, hair and nail supplements, or multivitamins containing > 5 mg/day) until at least 12 hours after the last biotin administration. If unsure, or if the clinical picture does not fit the results please contact the laboratory . We have methods to check for biotin interference as well as for any other interferences and for the accuracy of the results.

Biotin interference would falsely decrease the result of this assay. 

Specimen Draw blood in a plasma gel tube (Li Hep – MMC preferred),
red-top or serum separator tube. Spin down and send 1 ml (minimum volume 0.5 ml) of specimen refrigerated.

If the specimen will not be delivered to the testing la within 8 hours of collection, send specimen FROZEN in plastic vial on dry ice.

CKMB stability is extremely temperature dependent. A CKMB decrease of > 10% can occur after the sample has stood for 1 hour at 32° C. 

Reference Values Males: < or = 7.7 ng/mL
Females: < or = 4.3 ng/mL 
Analytic Time 9 minutes upon receipt of specimen 
Day(s) Test Set Up Sunday through Saturday 
CPT Code(s) 82553