|Test Code||CAPOC / 180-IG|
|Test||CHROMOSOME ANALYSIS POC|
|Methodology||Chromosome Analysis (from live cells).|
|Description||Indications for cytogenetic analysis on POC include: history of more than two miscarriages, abnormalities on ultrasound prior to pregnancy loss, confirmation of abnormal prenatal results or pregnancy loss after IVF. Abnormal POC cytogenetic results may preclude the need for extensive infertility evaluation. The diagnosis of a chromosome abnormality may be important in the management of future pregnancies.|
|Specimen||Please Note: In the absence of Integrated Genetics tubes, use any sterile screw-top container with tissue culture medium, Hanks Balanced Salt Solution or Earls and add antibiotics: Penicillin/Streptomycin (100 IU/ml/100 µg/ml) or Gentamycin (50 µg/ml). If the Integrated Genetics media has expired, please ship the specimen in the expired media, as it is preferable to any other types of tissue culture media.
•Laboratory-provided screw-top tubes with sterile transport medium.
•Obtain POC’s using a sterile technique. Snip tissue using sterile scissors, etc. Cover specimen with sterile gauze to prevent contamination from airborne bacteria.
•Placenta – Tissue that contains chorionic villi (has 90% success rate)
|Reference Values||See Report|
|Analytic Time||7 - 21 Days (average 10 days)|
|Day(s) Test Set Up||Monday through Saturday|
88233 Tissue biopsy
88262 Chromosome analysis, POC
88291 Interpretation and report