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86213M
HYPEROXALURIA PANEL, URINE

Test Code 86213M 
Test HYPEROXALURIA PANEL, URINE 
Methodology Gas Chromatography/Mass Spectrometry (GC/MS) 
Description Useful for distinguishing between primary and secondary hyperoxaluria, and between type I and type II primary hyperoxaluria. 
Specimen Send 10 mL (minimum 1.1mL) from a random urine collection. Patient must be fasting-overnight (12-14 hours)
1. Have patient void the first-morning specimen.
2. Collect specimen within 2 hours of first-morning void while patient continues to fast. Fluids are allowed.
3. Immediately freeze specimen. 
Reference Values GLYCOLATE
0-31 days: 0-57 ug/mg creatinine
1-5 months: 0-54 ug/mg creatinine
6-12 months: 0-60 ug/mg creatinine
1-5 years: 0-89 ug/mg creatinine
>or= 6 years: 0-78 ug/mg creatinine

GLYCERATE
0-31 days: 0-38 ug/mg creatinine
1-5 months: 0-71 ug/mg creatinine
6-12 months: 0-56 ug/mg creatinine
1-5 years: 0-17 ug/mg creatinine
>or= 6 years: 0-8 ug/mg creatinine

OXALATE
0-31 days: 0-301 ug/mg creatinine
1-5 months: 0-398 ug/mg creatinine
6-12 months: 0-280 ug/mg creatinine
1-5 years: 0-128 ug/mg creatinine
6-10 years: 0-72 ug/mg creatinine
> or = 11 years: 0-56 ug/mg creatinine

GLYOXYLATE
0-31 days: 0.0-7.9 ug/mg creatinine
1-5 months: 0.0-11.4 ug/mg creatinine
6-12 months: 0.0-5.5 ug/mg creatinine
1-5 years: 0.0-3.9 ug/mg creatinine
> or = 6 years: 0.0-2.9 ug/mg creatinine

Interpretation:
Increased concentrations of oxalate and glycolate indicate type I hyperoxaluria.
Increased concentrations of oxalate and glycerate indicate type II hyperoxaluria.
Increased concentrations of oxalate with normal concentrations of glycolate and glycerate indicate secondary hyperoxaluria.

NOTE: Ascorbic acid will falsely elevate oxalic acid results. 

Analytic Time 14 Days 
Day(s) Test Set Up Varies; 1 time per month 
CPT Code(s) 82544