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RGBS
CULTURE, GROUP B STREPTOCOCCUS W/SUSCEPTIBILITY

Test Code RGBS 
Test CULTURE, GROUP B STREPTOCOCCUS w/SUSCEPTIBILITY 
Methodology Conventional Culture 
Description Use for prenatal screening for Group B Streptococcus when antibitic susceptibiilty testing is required.

Indications:
Group B Streptococci are universally susceptible to penicillin, ampicillin and cefazolin. Guidelines published jointly by the Centers for Disease Control and Prevention, American College of Obstetricians and Gynecologists and the American Academy of Pediatrics recommend treatment of most patients during labor with one of these antibiotics.

Antibiotic susceptibility testing is only recommended for patients who are allergic to penicillin and who are at high risk of anaphylaxis if treated with one of these antibiotics. The guidelines define patients at high risk of anaphylaxis due to penicillin allergy as “those who have experienced immediate hypersensitivity to penicillin including a history of penicillin-related anaphylaxis; other high risk patients are those with asthma or other diseases that would make anaphylaxis more dangerous or difficult to treat, such as persons being treated with beta-adrenergic-blocking agents.”

The guidelines recommend intrapartum treatment of patients at high risk of anaphylaxis with clindamycin or erythromycin if the organism tests susceptible to both antibiotics. If the organism is resistant to either clindamycin or erythromycin, treatment with vancomycin will be necessary.

See also: CULTURE, GROUP B STREPTOCOCCUS (GBSCR) 

Specimen 1. Do not use a speculum when sampling vagina.
2. Swab vaginal introitus and rectum with a single swab.
3. Place swab in a culture transport media tube.
4. If detection of any other genital pathogens is desired, use a speculum to collect an additional specimen.
5. Label tube with patient’s name (first and last), date of birth or medical record number, date and time of collection, collector’s initials and specimen source.
6. Maintain sterility and forward promptly at ambient temperature only. Do not refrigerate.

NOTE: SPECIMEN SOURCE IS REQUIRED ON REQUEST FORM FOR PROCESSING. 

Reference Values No Group B Strep isolated 
Analytic Time 4 Days 
Day(s) Test Set Up Monday through Sunday 
CPT Code(s) 87070  Culture, bacteria
87184  Antibiotic susceptibility (Disk Diffusion), if indicated