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CNAB / ANCA-M
CYTOPLASMIC NEUTROPHIL ANTIBODIES, SERUM

Test Code CNAB / ANCA-M 
Test CYTOPLASMIC NEUTROPHIL ANTIBODIES, SERUM 
Methodology Indirect Immunofluorescence 
Description Useful for: Antineutrophil cytoplasmic antibodies (cANCA and pANCA): evaluating patients suspected of having autoimmune vasculitis (both Wegener granulomatosis and microscopic polyangiitis)

cANCA titer: may be useful for monitoring treatment response in patients with WG (systemic or organ-limited disease); increasing titer suggests relapse of disease, while a decreasing titer suggests successful treatment 

Specimen Draw blood in a plain, red-top tube(s) or a serum gel tube(s). Spin down and send 0.5 mL (minimum: 0.2 mL) of serum refrigerated. 
Reference Values Negative
If positive for cANCA, results are titered 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday, Sunday 
CPT Code(s) 86255  Screen
86256  Titer, if indicated