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HCGTM / BHCG-M
HCG, BETA SUBUNIT (BHCG), TUMOR MARKER, SERUM

Test Code HCGTM / BHCG-M 
Test HCG, BETA SUBUNIT (bHCG), TUMOR MARKER, SERUM 
Methodology Electrochemiluminescence ImmunoAssay 
Description Useful For: Monitoring patients for retained products of conception
An aid in the diagnosis of gestational trophoblastic disease (GTD), testicular tumors, ovarian germ cell tumors, teratomas, and, rarely, other human chorionic gonadotropin (hCG)-secreting tumors
Serial measurement of hCG following treatment to:
-Monitor therapeutic response in GTD or in hCG-secreting tumors
-Detect persistent or recurrent GTD or hCG-secreting tumors

NOTE: This assay is not meant to be used for pregnancy testing.

NOTE: This test, when ordered on Medicare patients, is subject to the National Coverage Determination (NCD) policy "Human Chorionic Gonadotropin". Please verify that the diagnosis code (ICD-9) you have chosen demonstrates medical necessity for the test as documented in the physician's patient record. The CMS web site or the NorDx Limited Coverage Documentation Guide are available to assist you with this verification. A properly executed Advance Beneficiary Notice (ABN) must be submitted with the specimen if medical necessity is not demonstrated by the ICD-9 code chosen. 

Specimen Draw blood in a plain red-top or serum gel tube. Spin down and send 1.0 mL (minimum: 0.5 mL) of serum refrigerated in a screw-capped, plastic vial. 
Reference Values Children(1,2)
Males
Birth-3 months: < or =50 IU/L*
>3 months-<18 years: <1.4 IU/L
Females
Birth-3 months: < or =50 IU/L*
>3 months-<18 years: <1.0 IU/L
*hCG, produced in the placenta, partially passes the placental barrier. Newborn serum beta-hCG concentrations are approximately 1/400th of the corresponding maternal serum concentrations, resulting in neonate beta-hCG levels of 10-50 IU/L at birth. Clearance half-life is approximately 2-3 days. Therefore, by 3 months of age, levels comparable to adults should be reached.

Adults (97.5th percentile)
Males: <1.4 IU/L
Females
Premenopausal, nonpregnant: <1.0 IU/L
Postmenopausal: <7.0 IU/L 
Analytic Time 1 Day 
Day(s) Test Set Up Monday through Saturday 
CPT Code(s) 84702