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ADH / AVP-M
ARGININE VASOPRESSIN, PLASMA

Test Code ADH / AVP-M 
Test ARGININE VASOPRESSIN, PLASMA 
Methodology Radioimmunoassay (RIA) 
Description Useful for diagnosis and characterization of diabetes insipidus, for diagnosis of psychogenic water intoxication and ectopic AVP production, particularly due to bronchogenic carcinoma, and as an adjunct in the diagnosis of inappropriate ADH syndronme, which results in dilutional hyponatremia 
Specimen 1. Have patient fast and thirst for 6 hours. No liquids, including water, are allowed.
2. Draw blood in a lavender-top (EDTA) tube and process 5.0 mL of EDTA whole blood as follows:
A. Spin down in a refrigerated centrifuge at approximately 1000 X G (2000 rpm for a 20 cm radius centrifuge) for 10 minutes.
B. Remove plasma, carefully avoiding the platelet/buffy coat.
3. Send 2.0 mL (minimum 1.2 mL) of EDTA platelet-poor plasma FROZEN in a screw-capped, plastic vial. (GLASS VIALS CANNOT BE ACCEPTED.) 
Reference Values Adults: < 1.7 pg/mL
Reference values were determined on platelet-poor EDTA plasma from individuals fasting no longer than overnight. 
Analytic Time 3 Days 
Day(s) Test Set Up Wednesday 
CPT Code(s) 84588