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AFPFL / AFPA-M
ALPHA-FETOPROTEIN (AFP), AMNIOTIC FLUID

Test Code AFPFL / AFPA-M 
Test ALPHA-FETOPROTEIN (AFP), AMNIOTIC FLUID 
Methodology Two-site Immunoenzymatic (Sandwich) Assay 
Description Useful as a screening test to detect open neural tube defects or other fetal abnormalities, and as a follow-up test for patients with elevated serum results or in conjunction with cytogenetic testing.
NOTE: If Alpha-Fetoprotein, AF is positive, then Acetylcholinesterase, AF is performed at an additional charge. 
Specimen 1.0 mL (minimum 0.5 mL) of amniotic fluid. DO NOT CENTRIFUGE. Send specimen refrigerated.

NOTE:
1. The following information is required for processing:
A. First day of last menstrual period
B. Date ultrasound performed
C. Gestational age by ultrasound
D. Collection date
2. Gestational age must be between 13 and 24 weeks; 16 - 18 weeks preferred.
3. If chromosome studies are also requested, see test #8426, "Chromosome Analysis, Amniotic Fluid". The specimen for AFP-AF, when requested with chromosome analysis, cannot be frozen.
4. Please complete a "Cytogenetics / AFP Congenital Disorders Request Form" and forward it with the specimen. 

Reference Values <= 2.0 multiples of median (MOM) for gestational group
Interpretive report will be supplied.
Abnormal results are called back to ordering physician. 
Analytic Time 1 Day 
Day(s) Test Set Up Monday through Saturday 
CPT Code(s) 82013  Acetylcholinesterase, if indicated
82106  Alpha-fetoprotein