|Test Code||AAQT / AAQP-M|
|Test||AMINO ACIDS QUANTITATIVE ION-EXCHANGE, PLASMA|
|Methodology||Quantitative Analysis by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Includes quantitation of the following amino acids: Taurine, Threonine, Serine, Asparagine, Glutamic Acid, Glutamine, Proline, Alanine, Citrulline, Alpha-amino-n-butyric acid, Valine, Cystine, Methionine, Isoleucine, Leucine, Tyrosine, Phenylalanine, Beta-alanine, Ornithine, Lysine, Histidine, Argininosuccinic Acid, Allo-isoleucine, Arginine,Phosphoserine, Phosphoethanolamine, Hydroxyproline, Glycine, Aspartic Acid, Ethanolamine, Sarcosine, 1-Methylhistidine, 3-Methylhistidine, Carnosine, Anserine, Homocitruline, Alpha-aminoadipic Acid, Gamma-amino-n-butyric acid, Beta-aminoisobutyric Acid, Hydroxylysine, Cystathioine and Tryptophan.
|Description||Inborn errors of amino acid metabolism can manifest themselves at any time in a person's life, but most become evident in infancy and early childhood. Affected patients may have failure to thrive, neurological symptoms, digestive problems, locomotor retardation, and a wide spectrum of laboratory findings. If not diagnosed promptly and treated properly, these disorders can result in poor growth, mental retardation, and death. Amino acid analysis may also have clinical importance in the evaluation of several acquired conditions, including endocrine disorders, liver diseases, muscle diseases, neoplastic diseases, neurological disorders, nutritional disturbances, renal failure, and burns.|
|Specimen||Draw blood in a green-top (sodium heparin) tube from a fasting patient (4 hours or more in infants). (THROMBIN-ACTIVATED TUBE IS NOT ACCEPTABLE.) Spin down promptly and send 0.5 mL (minimum: 0.3 mL) of heparinized plasma FROZEN in plastic vial on dry ice.
NOTE: Include patient's age, sex, family history, clinical condition (asymptomatic or acute episode), diet, and drug therapy information.
|Reference Values||Amino Acids Plasma Reference Ranges|
|Analytic Time||3 Days|
|Day(s) Test Set Up||Monday through Friday|