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FSC-M
FUNGAL ANTIBODY SURVEY, CSF

Test Code FSC-M 
Test FUNGAL ANTIBODY SURVEY, CSF 
Methodology - Complement Fixation (CF) Using Coccidioidin:
IgG/Immunodiffusion: IgG and IgM
- Enzyme Immunoassay (EIA)
- Complement Fixation (CF)/Immunodiffusion
- Latex Agglutination 
Description Includes blastomyces, coccidioides, histoplasma antibodies, and cryptococcus antigen. If Cryptococcus Antigen screen is equivocal or positive by EIA, latex agglutination testing will be performed at an additional charge. 
Specimen 3.0 mL (minimum volume: 2.3 mL) spinal fluid. Send specimen refrigerated in a screw-capped, round-bottom, plastic vial. Forward promptly. 
Reference Values Blastomyces ANTIBODY BY EIA
Negative

Coccidioides ANTIBODY
Complement fixation: negative
If positive, results are titered.
Immunodiffusion: negative
Results are reported as positive, negative, or equivocal.

Cryptococcus ANTIGEN SCREEN
Negative
If positive, results are titered under the reflex test.

Histoplasma ANTIBODY
Mycelial by complement fixation: negative
Positives are reported as titer.
Yeast by complement fixation: negative
Positives are reported as titer.
Antibody by immunodiffusion: negative
Positives are reported as band present. 
Analytic Time 3 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 86403  Cryptococcus latex agglutination (if appropriate)
86612  Blastomyces antibody
86635 x 3  Coccidioides, antibody
86698 x 3  Histoplasma antibody
87327  Cryptococcus antigen