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IMIP / IMIPR-M
IMIPRAMINE AND DESIPRAMINE, S

Test Code IMIP / IMIPR-M 
Test IMIPRAMINE AND DESIPRAMINE, S 
Methodology High-Performance Liquid Chromatography (HPLC) 
Description Imipramine is used for relief of symptoms of endogenous depression requiring 1 - 3 weeks of treatment before therapeutic effectiveness becomes apparent.
Desipramine is used for endogenous depression when the patient needs a drug with significant stimulatory side effects. 
Specimen Draw blood in a plain, red-top tube. (SERUM GEL TUBE IS NOT ACCEPTABLE.) Spin down and send 2.0 mL (minimum: 1.0 mL) of serum refrigerated. 
Reference Values IMIPRAMINE and DESIPRAMINE
Total therapeutic concentration: 175 - 300 ng/mL
Total toxic concentration: > or = 300 ng/mL

DESIPRAMINE ONLY
Therapeutic concentration: 100 - 300 ng/mL
Toxic concentration: > or = 300 ng/Ml 

Analytic Time 1 Day 
Day(s) Test Set Up Monday through Friday, Sunday 
CPT Code(s) 80335  
G0480 or  G0481 or G0482 or G0483, Drug test(s), definitive (Government payers, if appropriate), if indicated