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APCD117
CD117 (C-KIT), IMMUNOHISTOCHEMISTRY STAIN

Test Code APCD117 
Test CD117 (c-kit), IMMUNOHISTOCHEMISTRY STAIN 
Description NORMAL CELLS
The strong positive c-kit immunoreactivity is observed in mast cells of epithelial and hematopoietic tissues. Glial cells both fetal and adult brain show positive staining, and also ductal cells in mammary glands demonstrate positive staining, whereas myoepithelial cells are negative. Additionally, medullary cells of the adrenal gland show strong nuclear staining (1).

TUMOR CELLS
High expressions of c-kit immunoreactivity is observed in lung cancer, especially small cell carcinoma.

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist. 

Specimen Formalin-fixed or paraffin-embedded tissue specimen. 
Reference Values An interpretive report will be issued. 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 88342