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APBCL-2
BCL-2, IMMUNOHISTOCHEMISTRY STAIN

Test Code APBCL-2 
Test BCL-2, IMMUNOHISTOCHEMISTRY STAIN 
Description Bcl-2 is detectable in neoplastic lymphoma cells in which the 14:18 chromosomal translocation is present. It has shown consistent negative staining of reactive germinal centers and positive staining of neoplastic follicles in follicular lymphoma. Therefore, Bcl-2 is useful in the distinction between follicular hyperplasia and follicular lymphoma. The Bcl-2 product is considered to act as an inhibitor of apoptosis.

NOTE: This test is usually ordered in conjunction with a pathology consultation. The pathology professional component will be billed separately by the consulting pathologist. 

Specimen Formalin-fixed or paraffin-embedded tissue specimen. 
Reference Values An interpretive report will be issued. 
Analytic Time 2 Days 
Day(s) Test Set Up Monday through Friday 
CPT Code(s) 88342